Crewed Space-Flights - United States (2001 - present)
- Space Shuttle Columbia (STS-107, 2003) - Tragically lost during re-entry.
- Space Shuttle Discovery (STS-114, 2005) - First Shuttle flight after Columbia disaster.
- Space Shuttle Atlantis (STS-115, 2006) - Resumption of ISS assembly after Columbia.
- STS-122 (2008) - European Space Agency's Columbus laboratory delivered to ISS.
- Expedition 34/35 (2012-2013) - Chris Hadfield's social media impact from the ISS.
- Expedition 42/43 (2014-2015) - Continued ISS crew rotation.
- Expedition 48/49 (2016) - One-Year Mission with Scott Kelly and Mikhail Kornienko.
- Crew Dragon Demo-2 (2020) - First crewed mission of the SpaceX Crew Dragon spacecraft to the ISS.
- Crew-1 (2020) - First operational mission of Crew Dragon to the ISS.
- Crew-2 (2021) - Second operational mission of Crew Dragon to the ISS.
- Ax-1 (2022) - First private mission to the ISS by Axiom Space.
- Inspiration4 (2021) - First all-civilian mission to orbit, launched by SpaceX.


